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SK-N-SH Cell Line

The SK-N-SH cell line was established in 1970 from the bone marrow metastasis of a 4-year-old female with neuroblastoma. SK-N-SH cells exhibit an epithelial morphology and adherent cultural properties. SK-N-SH is capable of differentiating and exhibiting neurite outgrowths. This hyperdiploid cell line has a modal chromosome number of 47 and is genetically female with two X chromosomes. SK-N-SH cells express blood type A and Rh+ , as well as produce high levels of dopamine-beta-hydroxylase. Pediatric brain cancer is one of the leading causes of cancer-related deaths in children under 20 years old, and neuroblastoma cell lines like SK-N-SH are valuable tools in preclinical research that allow scientists to develop new drugs and treatments. A pre-optimized SK-N-SH transfection reagent  to transfect SK-N-SH cells and conduct brain cancer research is commercially available from Altogen Biosystems . SK-N-SH cells can also be used to study neural pathways. Past studies h...
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Brain Cancer Xenografts and Custom Research from Altogen

Altogen Biosystems is a quality producer and custom research organization for genetic research. Custom biological products and other experiments include siRNA screening, optimization of preclinical research, stable transfection of cells, RNAi testing and more. Dedicated to benefiting researchers with state-of-the-art and specialized services, Altogen Biosystems aims to further modern clinical discoveries. Visit Altogen Biosystems’ catalog for custom brain cancer xenograft models .
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SK-N-SH Cells for Brain Cancer Drug Studies

Derived from the metastasized neuroblastoma of a young human female, the SK-N-SH cell line is one of the primary in vitro models for brain cancer drug development and testing of novel immunotherapies. With neurite outgrowths and modulated differentiation, SK-N-SH complement dopamine-beta-hydroxylase expression with a physiology that closely follows that of live neuroblastoma tissue in vivo . With cancer-specific transfection reagents , research involving the screening of siRNA sequences can show how RNA interference technology could be used to combat cancer proliferation even after metastasis.
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SK-N-SH Transfection Reagent (Neuroblastoma Cells, HTB-11)

The SK-N-SH cell line was isolated in 1970 from the brain tissue extracted from a 4-year-old female patient suffering from a neuroblastoma. These cells are ideal as transfection hosts because they are known to express high levels of dopamine-beta-hydroxylase and having a higher doubling time. SK-N-SH are used in biomedical research for certain types of brain cancer. Altogen Biosystems  manufactures and prepares a SK-N-SH transfection reagent that is cationic lipid based with a high transfection efficacy. This reagent is proven to establish stable cell lines for reliable yields.   Transfection Reagent for SK-N-SH Cells (Neuroblastoma Cells, HTB-11)
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