Altogen
Biosystems is a quality producer and custom research organization for genetic
research. Custom biological products and other experiments include siRNA
screening, optimization of preclinical research, stable transfection of cells,
RNAi testing and more. Dedicated to benefiting researchers with
state-of-the-art and specialized services, Altogen Biosystems aims to further
modern clinical discoveries. Visit Altogen Biosystems’ catalog for custom brain
cancer xenograft models.
The SK-N-SH cell line was established in 1970 from the bone marrow metastasis of a 4-year-old female with neuroblastoma. SK-N-SH cells exhibit an epithelial morphology and adherent cultural properties. SK-N-SH is capable of differentiating and exhibiting neurite outgrowths. This hyperdiploid cell line has a modal chromosome number of 47 and is genetically female with two X chromosomes. SK-N-SH cells express blood type A and Rh+ , as well as produce high levels of dopamine-beta-hydroxylase. Pediatric brain cancer is one of the leading causes of cancer-related deaths in children under 20 years old, and neuroblastoma cell lines like SK-N-SH are valuable tools in preclinical research that allow scientists to develop new drugs and treatments. A pre-optimized SK-N-SH transfection reagent to transfect SK-N-SH cells and conduct brain cancer research is commercially available from Altogen Biosystems . SK-N-SH cells can also be used to study neural pathways. Past studies h...
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